Frédéric Charlotte Selected Research

Histiocytosis

1/2017	Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells.
1/2017	High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis.
1/2017	Histiocytoses: emerging neoplasia behind inflammation.
2/2013	Dramatic efficacy of vemurafenib in both multisystemic and refractory Erdheim-Chester disease and Langerhans cell histiocytosis harboring the BRAF V600E mutation.
9/2012	High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses.
6/2008	Imatinib mesylate for platelet-derived growth factor receptor-beta-positive Erdheim-Chester histiocytosis.

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Frédéric Charlotte Research Topics

Disease

13	Fibrosis (Cirrhosis) 12/2020 - 07/2002
11	Infections 01/2021 - 11/2002
11	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020 - 09/2002
10	Neoplasms (Cancer) 01/2021 - 01/2002
9	Erdheim-Chester Disease 11/2019 - 03/2011
8	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2020 - 12/2003
6	Lymphoma (Lymphomas) 01/2019 - 11/2006
6	Histiocytosis 01/2017 - 06/2008
5	Liver Diseases (Liver Disease) 02/2009 - 07/2002
4	Inflammation (Inflammations) 01/2020 - 07/2006
4	Hepatitis C 01/2016 - 09/2002
3	Insulin Resistance 12/2020 - 02/2009
3	Cryoglobulinemia 03/2015 - 11/2004
3	Vasculitis (Vasculitides) 12/2010 - 06/2006
3	Chronic Hepatitis C 07/2006 - 09/2002
2	Fatty Liver 01/2020 - 06/2006
2	Non-alcoholic Fatty Liver Disease 01/2020 - 05/2015
2	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2019 - 06/2006
2	Waldenstrom Macroglobulinemia (Macroglobulinemia) 01/2019 - 01/2016
2	Non-Langerhans-Cell Histiocytosis (Histiocytosis, Non Langerhans Cell) 01/2018 - 01/2017
2	Alcoholic Liver Cirrhosis (Alcoholic Cirrhosis) 01/2017 - 04/2015
2	Chronic Hepatitis (Chronic Active Hepatitis) 01/2017 - 07/2002
2	Carcinoma (Carcinomatosis) 04/2015 - 01/2007
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 12/2010 - 09/2004
2	Neoplasm Metastasis (Metastasis) 06/2007 - 01/2007
1	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 08/2022
1	COVID-19 01/2022
1	Pneumonia (Pneumonitis) 01/2022
1	Lymphocytosis 01/2022
1	Cholangiocarcinoma 01/2022
1	Glioma (Gliomas) 01/2021
1	Lung Neoplasms (Lung Cancer) 01/2021
1	Weight Gain 12/2020
1	Hypertrophy 01/2020
1	Abdominal Obesity 01/2020
1	Lung Diseases (Lung Disease) 01/2020
1	Hematologic Diseases (Blood Diseases) 01/2020
1	Alcoholic Fatty Liver 01/2020
1	Splenomegaly 01/2018
1	Hypoalphalipoproteinemias (Hypoalphalipoproteinemia) 01/2018
1	Virus Diseases (Viral Diseases) 01/2017
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2016
1	Overweight 05/2015
1	Hepatocellular Carcinoma (Hepatoma) 05/2015
1	Hypertension (High Blood Pressure) 05/2015

Drug/Important Bio-Agent (IBA)

5	Biological ProductsIBA 10/2020 - 07/2006
5	Biomarkers (Surrogate Marker)IBA 12/2010 - 09/2002
4	CryoglobulinsIBA 01/2018 - 11/2004
3	Antiviral Agents (Antivirals)IBA 01/2022 - 03/2015
3	Proteins (Proteins, Gene)FDA Link 01/2016 - 03/2015
3	VemurafenibIBA 02/2015 - 09/2012
2	SteroidsIBA 01/2022 - 04/2004
2	Transaminases (Aminotransferases)IBA 01/2020 - 02/2009
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2020 - 11/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 05/2011
2	AntigensIBA 01/2019 - 12/2006
2	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 11/2006
2	LipidsIBA 01/2018 - 04/2014
2	Phosphotransferases (Kinase)IBA 01/2017 - 01/2017
2	BilirubinIBA 04/2015 - 01/2003
2	RNA (Ribonucleic Acid)IBA 02/2009 - 07/2002
2	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 06/2006 - 01/2003
1	Cell-Free Nucleic AcidsIBA 01/2021
1	apremilastIBA 01/2021
1	Integrase InhibitorsIBA 12/2020
1	dolutegravirIBA 12/2020
1	Raltegravir Potassium FDA Link 12/2020
1	IntegrasesIBA 12/2020
1	Amino Acids FDA Link 01/2020
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2020
1	Syntex adjuvant formulationIBA 01/2020
1	cobimetinibIBA 01/2020
1	Insulin (Novolin)FDA Link 01/2020
1	RetinoidsIBA 01/2020
1	CollagenIBA 01/2020
1	Choline (Choline Chloride)IBA 01/2020
1	Transcription Factors (Transcription Factor)IBA 01/2019
1	Proto-Oncogene Proteins c-etsIBA 01/2019
1	Complementarity Determining Regions (Complementarity Determining Region)IBA 01/2019
1	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 01/2018
1	Infliximab (Remicade)FDA Link 01/2018
1	Sodium Glutamate (Accent)IBA 01/2018
1	HDL CholesterolIBA 01/2018
1	Ribavirin (Virazole)FDA LinkGeneric 01/2017
1	Mitogen-Activated Protein KinasesIBA 01/2017
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 03/2016
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 03/2016
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2016
1	Immunoglobulin M (IgM)IBA 12/2015
1	Adrenal Cortex Hormones (Corticosteroids)IBA 12/2015
1	Immunoglobulin G (IgG)IBA 12/2015

Therapy/Procedure

9	Therapeutics 01/2017 - 09/2004
5	Hematopoietic Stem Cell Transplantation 01/2018 - 12/2003
4	Liver Transplantation 01/2017 - 01/2010
3	Drug Therapy (Chemotherapy) 08/2022 - 01/2002
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2020 - 01/2006
2	Transjugular Intrahepatic Portasystemic Shunt 01/2019 - 01/2010
2	Aftercare (After-Treatment) 02/2013 - 06/2006
1	Immunotherapy 01/2022
1	Heterologous Transplantation (Xenotransplantation) 01/2017